What are the Fragile X Associated Disorders (FXAD)?
It’s a family of disorders that affect men and women with either the pre or full mutation of the fragile x gene. Approximately 1 in 800 men and 1 in 260 women in the world are carriers.
Fragile X Syndrome (FXS)
- The leading known genetic cause of intellectual disability resulting from a full mutation of the fragile X gene.
Autism Spectrum Disorder Associated with FXS (ASD)
- The only known genetic cause of autism resulting from a full mutation of the Fragile X gene.
Fragile X Associated Primary Ovarian Insufficiency (FXPOI)
- Early menopause and decreased fertility resulting from a premutaion of the fragile X gene.
Fragile X Associated Tremor/Ataxia Syndrome (FXTAS)
- Neurological condition resulting in Parkinson’s like tremors and balance and memory problems resulting from a premutation of the Fragile X gene.
Please visit the National Fragile X Foundation for more information.
